A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population

Table 2

Genotype and allele frequencies of rs7799039 (LEP − 2548G/A) and rs2167270 (+19G/A) SNPs in case and control subjects.

SNP ID	Allele/genotype	Control, n (%)	Case, n (%)	χ^2	value
rs7799039 − 2548 A/G	A	88(0.656)	108(0.666)	0.03	0.90
	G	46(0.434)	54(0.333)
	AA	20(0.298)	27(0.333)	0.35	0.84
	AG	33(0.492)	36(0.444)
	GG	14(0.208)	18(0.222)
rs2167270 + 19G/A	G	68(0.666)	70(0.673)	0.01	0.92
	A	34(0.333)	34(0.326)
	GG	22(0.431)	23(0.442)	0.01	0.91
	GA	29(0.569)	29(0.558)
	AA	—	—

Data expressed as number (frequency). χ² estimated with 2df for genotypes and 1df for alleles.