Research Article

A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population

Table 3

Adiposity measures and serum leptin level of subjects with LEP SNPs.

SNPsID No.GenotypeAge/sexBMI (kg/m2)WHRBF (%)Leptin (ng/ml)Family history of obesity

rs570757178C063CG36/F23.30.9133.827.1No
C155CG41/M23.41.0329.84.36No
P288CG38/M27.60.9322.519.7No
P291CG40/M26.31.0128.17.41No

rs6976701P055AG35/M28.61.0427.340.7No
P203AG35/M25.10.9121.620.6No
P286AG43/M280.9226.415.9Yes (both parents)
P288AG27/M27.60.9322.519.7Yes (both parents)
P289AG51/M35.40.9636.925.6No
P292AA29/M25.20.9227.813.2Yes (both parents)

rs142904532 Thr 5 ThrP184CG54/M44.81.054137Yes (both parents)

rs201067336 Phe 17 LeuP169GT39/F27.90.94289.3No
P202GT26/M25.20.9231.8No

rs111650508 Lys36ArgP171AG51/M26.91.0326.6Yes (mother)

rs28954114P076GA25/F27.30.9235.946.4Yes (mother)
C145GA37/F17.50.8228.65.01No
C248GA22/M16.80.959.552.0No

Study subjects identification number is given with “C” or “P” as prefix. “C” represents control and “P” case (people with obesity).