The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity

Table 4

Comparison of PS, ADAM17, TNF-α, and sMER based on WC ranges.

Variables	Group				a	b	c	d	e
	Control (n = 29)	Obese 1 (WC 91–110 cm) (n = 17)	Obese 2 (WC 110–120 cm) (n = 22)	Obese 3 (WC > 120 cm) (n = 17)
PS (ng/mL)	153.2 ± 15.6	135.4 ± 18.0	170.4 ± 16.9	285.0 ± 34.9	0.240	0.749	0.003	0.147	0.014
ADAM17 (kg/m^2)	143.2 ± 59.8	400.9 ± 142.3	643.1 ± 198.7	2700.1 ± 679.4	0.011	<0.001	<0.001	0.404	0.015
TNF-α (pg/mL)	1.2 ± 0.1	1.2 ± 0.9	1.1 ± 0.8	1.6 ± 0.2	0.216	0.159	0.083	0.863	0.009
sMER (pg/mL)	546.2 ± 163.1	514.6 ± 82.9	406.3 ± 45.2	967.6 ± 272.8	0.825	0.825	0.026	0.343	0.007

All results are expressed as mean ± SEM. Obese 1, waist circumference 91–110 cm; obese 2, waist circumference 110–120 cm; obese 3, waist circumference >120 cm; ^acomparison of confidence interval between the control group and obese 1 group; ^bcomparison of confidence interval between the control group and obese 2 group; ^ccomparison of confidence interval between the control group and obese 3 group; ^dcomparison of confidence interval between the obese 1 and obese 2 groups; ^ecomparison of confidence interval between the obese 2 and obese 3 groups. Significant in the 95% confidence interval () using the Mann–Whitney test.