Risk Factors for Age-Related Maculopathy

Table 6

Studies investigating the relationship between obesity and risk for ARM.

Study	No. of cases	Measure of risk factor	Type of ARM	Odds ratio or relative risk	95% confidence interval
Cross-Sectional Studies
Beaver Dam Eye Study [128]	4926	BMI	Neovascular AMD	1.02	0.97–1.08
			Geographic atrophy	1.06	0.98–1.14
Blue Mountains Eye Study [26]	3654	BMI > 30	Early ARM	1.78	1.19–2.68
		BMI < 20	Early ARM	1.92	1.16–3.18
Pathologies Oculaires Liees a L’Age [163]	2584	BMI > 30	Late ARM	2.29	1.00–5.23
			Retinal pigmentary abnormalities	1.54	1.05–2.26
Prospective Studies
Beaver Dam Eye Study [18, 20, 125]	3583	BMI	Retinal Pigmentary Abnormalities	1.03	1.00–1.06
Pooled data: Beaver Dam Eye Study/Blue Mountains Eye Study/Rotterdam Study [26]	9523	BMI > 30	Late ARM	0.87	0.51–1.47