Human Genetics of Diabetic Retinopathy: Current Perspectives

Table 1

Familial clustering of DR.

Type of Diabetes	Patients/Study	Evidence for familiar Clustering	Reference
Type 1	DCCT subjects	OR  =  3.1, 95% CI  =  1.2–7.8	[9]
Type 1	FinnDiane Study	OR  =  2.76, 95% CI  =  1.25–6.11, Heritability = 52%	[13]
Type 2	Asian Indians	OR  =  3.37, 95% CI  =  1.56–7.29	[10]
Type 2	Mexican Americans	OR  =  1.72, 95% CI  =  1.03–2.88	[11]
Type 2	Find-Eye Study	Heritability = 27%	[12]