Therapeutic Effect of Oral Bisphosphonates on Choroidal Neovascularization in the Human Eye
Figure 6
A 79-year-old male who received PDT for 27 months ago showed a recurrence of CNV (arrowheads), mainly at the temporal edge of the old scar (arrows) (a). Fluorescein angiography (FA) showed predominantly classic CNV (c), and optical coherence tomography (OCT) revealed a subretinal lesion before treatment (e). After the oral administration of alendronate for three months, the CNV became subretinal fibrosis (b) and no leakage was observed using FA (d). A remarkable decrease in the size of the subretinal lesion was observed using OCT (f).
