Pathophysiological Characteristics of Diabetic Ocular Complications in Spontaneously Diabetic Torii Rat

Figure 1

Nonfasting plasma insulin and glucose levels in Spontaneously Diabetic Torii (SDT) rats and control Sprague-Dawley (SD) rats. Diminish of pancreatic $\beta$-cells evokes hypoinsulinemia (a) and subsequent severe hyperglycemia (b) in SDT rats. Plasma glucose levels sharply increase at 15–20 weeks of age and eventually reach a plateau, approximately 800 mg/dL. Each value represents mean $\pm$ S.E.M. (N = 6–8).

(a)

(b)