Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression

Table 1

Comparison of characteristics of patients treated with DTFC and LTFC.

Characteristics	DTFC	LTFC	𝑃 value; (t-test)
Age	56.93 (9.54)	59.33 (7.7)	.455
CCT (μ)	548.03 (39.86)	549.65 (41.71)	.914
C/D ratio	0.62 (0.14)	0.65 (0.15)	.576
SBP mmHg baseline	157.70 (14.90)	146.70 (20.22)	.101
1 month	152.73 (16.90)	136.00 (13.67)	.006*
6 months	161.80 (18.40)*	146.800 (15.40)*	.022*
12 months	148.500 (11.18)	144.200 (17.41)	.428
18 months	158.63 (14.24)	141.10 (15.21)	.003*
DBP mmHg baseline	92.13 (8.12)	86.80 (7.53)	.073
1 month	93.73 (15.41)	81.10 (7.04)	.009*
6 months	97.43 (12.19)*	86.87 (9.49)*	.013*
12 months	91.07 (8.47)	86.57 (9.10)	.172
18 months	88.80 (5.81)	83.83 (8.41)	.070
IOP mmHg baseline	22.10 (2.69)	20.57 (3.25)	.171
1 month	16.33 (2.11)	14.90 (2.69)	.116
6 months	16.17 (2.81)	14.70 (2.57)	.147
12 months	17.10 (2.42)	15.13 (3.42)	.080
18 months	16.17 (2.08)	15.70 (3.38)	.653
OPP mmHg baseline	53.8933 (5.61)	50.6100 (7.52)	.186
1 month	59.27 (9.70)*	51.47 (4.6)*	.011*
6 months	62.93 (8.98)*	56.33 (5.84)*	.024*
12 months	56.38 (6.19)	55.38 (6.92)	.683
18 months	57.56 (3.81)	52.18 (7.26)	.019*
SPP mmHg baseline	135.60 (7.40)	126.13 (10.51)	.008*
1 month	136.40 (12.1)	121.10 (7.5)	.003*
6 months	145.63 (19.6)	132.10 (8.4)	.020*
12 months	131.4 (8.25)	129.07 (10.24)	.498
18 months	142.46 (7.4)	125.40 (9.34)	.0001*
DPP mmHg baseline	70.03 (7.40)	66.23 (8.11)	.191
1 month	77.20 (15.12)*	66.73 (5.35)*	.021*
6 months	81.33 (12.19)*	71.67 (7.95)*	.016*
12 months	73.97 (8.41)	71.43 (8.90)	.430
18 months	72.97 (6.15)	66.03 (11.03)	.045*

* 𝑃<.05 statistically significant.
DTFC: dorzolamide/timolol fixed combination; LTFC: latanoprost/timolol fixed combination; CCT: central corneal thickness; C/D ratio: clinically determined cup-disc ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; IOP: intraocular pressure; OPP: ocular perfusion pressure; DPP: diastolic perfusion pressure.