Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression

Table 2

Color Doppler imaging parameters during 18 months of followup.

Characteristics		DTFC	LTFC	𝑃 value; (t-test)
OA_PSV (cm/s)	Baseline	23.79 (8.837)	30.86 (9.30)	.042
	1 month	37.10 (12.33)	36.04 (7.83)	.781
	6 months	38.15 (16.24)	33.87 (8.27)	.371
	12 months	40.66 (15.51)	42.50 (14.01)	.736
	18 months	33.70 (10.05)	28.71 (6.93)	.125
OA_EDV (cm/s)	Baseline	4.82 (2.47)	7.03 (3.60)	.06
	1 month	8.22 (4.22)	8.78 (3.94)	.710
	6 months	8.87 (6.03)	7.66 (2.52)	.479
	12 months	10.59 (4.79)	9.63 (5.11)	.599
	18 months	9.47 (6.19)	7.23 (4.54)	.268
OA_RI	Baseline	0.79 (0.11)	0.76 (0.11)	.437
	1 month	0.79 (0.07)	0.75 (0.11)	.158
	6 months	0.76 (0.11 )	0.76 (0.09)	.986
	12 months	0.72 (0.12)	0.82 (0.17)	.046*
	18 months	0.76 (0.10)	0.87 (0.28)	.189
CRA_PSV (cm/s)	Baseline	15.09 (3.78)	17.91 (7.80)	.218
	1 month	17.78 (4.43)	18.59 (7.34)	.716
	6 months	19.08 (7.59)	17.67 (5.95)	.575
	12 months	28.88 (13.40)	22.71 (12.82)	.208
	18 months	18.69 (8.79)	17.46 (5.24)	.645
CRA_EDV (cm/s)	Baseline	4.56 (1.81)	6.33 (2.48)	.034*
	1 month	6.49 (2.22)	5.41 (3.19)	.291
	6 months	6.0 (2.49)	6.16 (2.64)	.868
	12 months	7.56 (3.67)	10.31 (7.34)	.204
	18 months	5.66 (2.80)	6.85 (3.24)	.289
CRA_RI	Baseline	0.80 (0.26)	0.81 (0.25)	.915
	1 months	0.68 (0.08)*	0.80 (0.16)*	.011*
	6 months	0.65 (0.082)	0.72 (0.19)	.192
	12 months	0.74 (0.19)	0.85 (0.19)	.000*
	18 months	0.67 (0.09)	0.93 (0.23)	.000*
SPCA_PSV (cm/s)	Baseline	15.55 (4.70)	14.50 (6.59)	.606
	1 month	15.95 (5.91)	13.38 (3.10)	.147
	6 months	20.03 (6.42)	17.92 (3.68)	.280
	12 months	21.01 (10.40)	19.81 (7.04)	.715
	18 months	13.69 (5.45)	11.03 (2.83)	.104
SPCA_EDV (cm/s)	Baseline	4.42 (2.29)	14.50 (6.59)	.973
	1 month	4.69 (2.28)	3.31 (2.11)	.095
	6 months	6.10 (2.16)	5.47 (2.22)	.442
	12 months	6.04 (2.67)*	3.43 (2.26)*	.007*
	18 months	4.39 (1.85)	3.87 (1.17)	.366
SPCA_RI	Baseline	0.71 (0.06)	0.79 (0.28)	.232
	1 month	0.75 (0.08)	0.79 (0.10)	.229
	6 months	0.69 (0.06)	0.69 (0.11)	.969
	12 months	0.70 (0.07)*	0.90 (0.27)*	.011*
	18 months	0.69 (0.11)*	0.85 (0.30)*	.015*

* 𝑃<.05 statistically significant.
DTFC: dorzolamide/timolol fixed combination; LTFC: latanoprost/timolol fixed combination; OA: ophthalmic artery; CRA: central retinal artery; SPCA: short posterior ciliary artery, PSV: peak systolic velocity; EDV: end diastolic velocity; RI: resistive index.