Clinical Study

Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression

Table 3

Pulsatile ocular blood flow parameters.

CharacteristicsDTFCLTFC value

IOP average (mmHg)baseline19.58 (3.68)20.96 (3.78).320
1 month17.12 (3.25)18.01 (2.83).429
6 months17.67 (3.73)17.71 (3.17).975
12 months17.87 (3.59)16.48 (2.56).231
18 months16.10 (2.78)15.23 (4.61).539

Pulse amplitudeBaseline4.17 (1.50)4.73 (1.58).335
1 month3.91 (0.88)3.95 (1.18).917
6 months4.93 (1.88)4.12 (1.47).201
12 months4.75 (1.40)4.67 (1.74).891
18 months4.73 (2.78)4.51 (1.42).675

Pulse volume (μL)Baseline7.19 (2.36)7.81 (2.68).507
1 month7.99 (2.27)7.60 (2.40).648
6 months8.91 (2.23)7.07 (3.26).417
12 months9.25 (1.95)*6.93 (3.20)*.025*
18 months9.29 (2.39)*7.82 (1.55).054*

POBF Baseline (μL/s)Baseline16.81 (4.53)17.57 (6.13).702
1 month19.12 (4.45)18.52 (5.48).754
6 months19.43 (4.54)18.63 (6.21).69
12 months20.87 (4.45)18.43 (6.51).242
18 months21.33 (2.74)19.75 (5.61).336

* statistically significant.
DTFC: dorzolamide/timolol fixed combination; LTFC: latanoprost/timolol fixed combination; IOP: intraocular pressure; POBF: pulsatile ocular blood flow.