Clinical Study

Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes

Table 1

Systemic and ocular parameters before and after topical application of nipradilol or placebo in controls.

ParameterNipradilolPlacebo
Before2 hrs ( )1 week ( )Before2 hrs ( )1 week ( )

Intraocular pressure (mmHg) (0.0047)* (0.0071)* (0.1212) (0.0144)*
Blood pressure
 Systolic (mmHg) (0.6542) (0.7550) (0.6542) (0.7550)
 Diastolic (mmHg) (0.9591) (0.8584) (0.9591) (0.8584)
Heart rate (beats/min) (0.1967) (0.1379) (0.1967) (0.1379)
Ocular perfusion pressure (mmHg) (0.0505) (0.2477) (0.3281) (0.4496)

Wilcoxon signed-rank sum test.
Values are presented as mean ± standard deviation.
.