Clinical Study

Early Responses to Intravitreal Ranibizumab in Typical Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

Table 1

Data summary of the participants stratified by AMD phenotype.

PCVtAMDtotal value
( )( ) ( )

Right eyes (%)15 (47%)12 (43%)27 (45%).96
Males (%)25 (78%)23 (82%)48 (80%).95
Mean age (±SD)Years74.6 (±9.0)74.4 (±9.2)74.5 (±9.0).93*
Baseline BCVA LogMAR (±SD)0.46 (±0.31)0.64 (±0.39)0.55 (±0.36).053*
Baseline CRT (±SD) μm414 (±191)374 (±109)395 (±158).34*
Baseline GLD (±SD) μm4558 (±1712)3530 (±996)4138 (±1479).0068*
Subretinal hemorrhage (>1 disc)9 (28%)5 (18%)14 (23%).34
BMI22.2 (±2.5)21.2 (±2.5)22.4 (±2.9).56*
Present or ever smoker20 (63%)21 (75%)41 (68%).45
Hypertension14 (44%)10 (36%)24 (40%).71
Diabetes mellitus5 (16%)6 (21%)11 (18%).81

GLD: greatest linear dimension, BCVA: best-corrected visual acuity, CRT: central retinal thickness, and BMI: body mass index. *Unpaired t-test; ×2 test.