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Journal of Ophthalmology
Volume 2011 (2011), Article ID 982410, 5 pages
Case Report

Toxic Anterior Segment Syndrome after Foldable Artiflex Iris-Fixated Phakic Intraocular Lens Implantation

Afdeling Oogheelkunde, Medisch Centrum Haaglanden, Lijnbaan 32, 2512 VA Den Haag, The Netherlands

Received 25 February 2011; Accepted 15 April 2011

Academic Editor: Gary Rubin

Copyright © 2011 Lucien A. M. van Philips. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Toxic anterior segment syndrome (TASS) developed in four cases after uneventful implantation of a foldable iris-fixated phakic intraocular lens (pIOL). Two cases occurred sequentially in one patient. The TASS subsided without complications in all cases after intensive topical steroid treatment. A multitude of possible causes is considered for the occurrence of these TASS cases. From the sterilization and cleaning of surgical instruments to the possibility of endotoxines in ophthalmic viscosurgical devices (OVD). These rare cases should alert the surgeon to the possibility of TASS after pIOL implantation.