Could Mineralocorticoids Play a Role in the Pathophysiology of Open Angle Glaucoma?

Figure 1

Immunohistochemical staining of the mouse anterior segment with antibodies against α-ENaC (a), β-ENaC (b), and γ-ENaC (c), immune sera were kindly provided by Bernard Rossier and Christoph Korbmacher, and without primary antibody (d). Note the intense staining of the trabecular meshwork (TM) and corneal endothelium (arrowheads) with α- and γ-ENaC, but not with β-ENaC. Arrows: conjunctiva and cornea epithelium. The conjunctiva did not show staining with antibodies against γ-ENaC (arrows in (c)).

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