The Role of Medications in Causing Dry Eye

Table 2

(a) 10-year incidence of dry eye in older population—relative risk due to medication (Beaver Dam Study [10]). (b) Association of dry eye in older population due to medication [11]**, [12]*.

(a)  

Drug	Relative risk	P value
Antihistamine use	1.24	0.05
Antianxiety drug use	1.43	0.02
Antidepressant use	1.44	0.03
Diuretic use	1.18	0.06
Oral steroid use	1.43	0.01
Vitamin use	1.30	0.02

(b)  

Drug	Odds ratio	95% confidence interval
Antiandrogen*	1.35	1.01–1.80
Antidepressants*	1.90	1.39–2.61
Aspirin**
(1/day)	1.07	0.69–1.67
(≥2/day)	1.98	1.36–2.89