Comparison of Newly Diagnosed Ocular Hypertension and Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity

Table 4

Summary of the Humphrey visual field test findings.

Variable	OAG	OH	Mean difference^a	𝑃-value^b
	𝑁=292	𝑁=113	(95% CI)
Mean fixation losses ± SD^c	9.3±13.2	7.0±9.6	2.3 (−0.1, 4.6)	0.058
Mean false positive rate ± SD	3.6±5.9	4.3±6.3	−0.71 (−2.1, 0.6)	0.299
Mean false negative rate ± SD	4.6±6.7	1.9±4.1	2.7 (1.6, 3.8)	<0.0001
Mean of mean deviation ± SD	−4.6±5.7	−0.4±1.6	−4.1 (−4.8, −3.4)	<0.0001
Mean pattern standard deviation ± SD	4.4±3.6	1.7±0.8	2.7 (2.3, 3.1)	<0.0001
Visual field unreliable, 𝑛 (%)	43 (14.7)	16 (14.2)	1.0 (0.6, 1.9)	0.885
Presence of artifacts, 𝑛 (%)^c	10 (3.4)	5 (4.5)	0.8 (0.3, 2.3)	0.625
Abnormal visual field overall, 𝑛 (%)^c	181 (62.2)	13 (11.6)	12.5 (6.7, 23.4)	<0.0001
Within 10° of fixation, 𝑛 (%)^d	134 (45.9)	27 (24.1)	2.7 (1.6, 4.4)	<0.0001
Glaucoma hemifield test outside normal limits, 𝑛 (%)^e	166 (59.1)	14 (13.0)	9.7 (5.3, 17.8)	<0.0001

Abbreviations: CI: confidence interval; 𝑛: number of subjects; OAG: open-angle glaucoma; OH: ocular hypertension; SD: standard deviation.
^aMean difference calculated as OAG−OH.
^bSignificance of differences between the OAG and OH groups was tested using the chi-square test for categorical data and the t-test for continuous data. Fisher’s exact test was used for categorical data when the expected marginal size was <5.
^cMissing data for 1 subject in both the OAG and OH groups.
^dMissing data for 1 subject in the OH group.
^en: 281 in the OAG and n: 108 in the OH group.