Clinical Study

Comparison of Newly Diagnosed Ocular Hypertension and Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity

Table 5

Summary of medical history, 𝑛 (%).

Medical history (past or current)OAGOHOdds ratio 𝑃 -valuea
𝑁 = 2 9 2 𝑁 = 1 1 3 (95% CI)

Vascular dysfunction128 (43.8)37 (32.7)1.6 (1.0, 2.5)0.042
Hypercholestero- lemia93 (31.8)31 (27.4)1.2 (0.8, 2.0)0.387
Smoking86 (29.5)53 (46.9)0.5 (0.3, 0.7)0.001
Migraine37 (12.7)16 (14.2)0.9 (0.5, 1.7)0.690
Thyroid disease34 (11.6)15 (13.3)0.9 (0.4, 1.7)0.652
Diabetes mellitus32 (11.0)17 (15.0)0.7 (0.4, 1.3)0.258
Pseudoexfoliation syndrome19 (6.5)3 (2.7)2.6 (0.7, 8.8)0.148
Raynaud’s disease15 (5.1)5 (4.4)1.2 (0.4, 3.3)0.767
Pigment dispersion syndrome12 (4.1)6 (5.3)0.8 (0.3, 2.1)0.599
Sleep apnea9 (3.1)7 (6.2)0.5 (0.2, 1.3)0.149

Abbreviations: CI = confidence interval; 𝑛 = number of subjects; OAG = open-angle glaucoma; OH = ocular hypertension.
aSignificance of differences between the OAG and OH groups was tested using the chi-square test; Fisher’s exact test was used when the expected marginal size was <5.