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Journal of Ophthalmology
Volume 2012 (2012), Article ID 852659, 6 pages
Review Article

Malignant Glaucoma: A Review of the Modern Literature

Oxford Eye Hospital, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK

Received 29 September 2011; Revised 11 December 2011; Accepted 9 January 2012

Academic Editor: Ian Grierson

Copyright © 2012 H. Shahid and J. F. Salmon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Malignant glaucoma is a rare form of glaucoma that typically follows surgery in patients with primary angle closure and primary angle-closure glaucoma. In this paper, the clinical features, classification, pathogenesis, and principles of management are discussed. Despite a high prevalence of primary angle closure glaucoma in South-East Asia, the vast majority of cases of malignant glaucoma are reported in White populations. This may reflect differing mechanisms of angle closure in White and Asian patients, which somehow reduces the likelihood of an aberrant relationship developing between the lens, ciliary body, anterior hyaloid, and vitreous structures within the eye. Although the exact underlying pathogenic mechanism remains unclear, the prognosis is good with modern medical, laser, and surgical treatment modalities.