Table of Contents Author Guidelines Submit a Manuscript
Journal of Ophthalmology
Volume 2013 (2013), Article ID 236371, 4 pages
Clinical Study

The Mean Platelet Volume in Patients with Retinal Vein Occlusion

Department of Ophthalmology, School of Medicine, Dicle University, 21280 Diyarbakır, Turkey

Received 18 December 2012; Revised 2 May 2013; Accepted 8 May 2013

Academic Editor: Michel Eid Farah

Copyright © 2013 Alparslan Şahin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The aim of this study was to investigate the mean platelet volume (MPV) of patients with retinal vein occlusion (RVO). Methods. Hundred and ninty-three patients with the diagnosis of RVO and 83 healthy control subjects were included in this retrospective study. Retinal vein occlusion was diagnosed based on clinical examination. All patients and control subjects underwent complete ocular examination. MPV, hematocrit, hemoglobin, and platelet count of the participants were recorded. The data of patients with RVO was compared with the control subjects. Results. Patients with RVO had significantly higher MPV values (  fL) compared with the control subjects (  fL) ( ). No significant difference was found in platelet counts between RVO group and the control group (  109/L and  109/L, resp., ), Mean platelet volume was an independent predictor of RVO (odds ratio (OR) = 1.43; 95% confidence interval (CI) = 1.09–1.89; ). Conclusion. Our results demonstrated that the MPV values were significantly higher in patients with RVO, suggesting that larger platelets may contribute to the pathogenesis of the RVOs.