Journal of Ophthalmology / 2013 / Article / Fig 5

Research Article

RNA Interference Targeting Connective Tissue Growth Factor Inhibits the Transforming Growth Factor-β2 Induced Proliferation in Human Tenon Capsule Fibroblasts

Figure 5

CTGF-siRNA reduces the viability of HTFs. Serum starved HTFs were transfected withCTGF-siRNA, control siRNA, or Lipofectamine 2000 before being stimulated with TGF-β 2 for 0, 24, 48, 72, and 96 h. The viability of HTFs was analyzed by CCK-8 assay. CTGF-siRNA suppressed the viability of TGF-β 2 stimulated cells at the time points of 48 h and 72 h, respectively. Data were from three experiments. * , ** .

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