RNA Interference Targeting Connective Tissue Growth Factor Inhibits the Transforming Growth Factor-β2 Induced Proliferation in Human Tenon Capsule Fibroblasts
Figure 5
CTGF-siRNA reduces the viability of HTFs. Serum starved HTFs were transfected withCTGF-siRNA, control siRNA, or Lipofectamine 2000 before being stimulated with TGF-β 2 for 0, 24, 48, 72, and 96 h. The viability of HTFs was analyzed by CCK-8 assay. CTGF-siRNA suppressed the viability of TGF-β 2 stimulated cells at the time points of 48 h and 72 h, respectively. Data were from three experiments. *, **.
