Grading of Age-Related Macular Degeneration: Comparison between Color Fundus Photography, Fluorescein Angiography, and Spectral Domain Optical Coherence Tomography

Table 2

Sensitivity and specificity in detecting AMD, CNV, and CNV activity.

	Color fundus photography	Fluorescein angiography	SDOCT
AMD; 𝑛 (sensitivity/specificity)	75 (gold standard)	77 (92%/82%)	78 (89%/76%)
CNV; 𝑛 (sensitivity/specificity)	53 (78%/100%)	68 (gold standard)	69 (94%/98%)
CNV activity; 𝑛 (sensitivity/specificity)	24 (38%/98%)	Ground truth used as gold standard (𝑛=60)
		53 (sensitivity 88%)	53 (sensitivity 88%)

AMD: age-related macular degeneration; CNV: choroidal neovascularization; and SDOCT: spectral-domain optical coherence tomography.