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Journal of Ophthalmology
Volume 2013, Article ID 398054, 4 pages
Clinical Study

Cellular Debris in the Anterior Vitreous in Silent Eyes of Behçet Patients as a Clue of Asymptomatic Ocular Involvement

1Department of Ophthalmology, Faculty of Medicine, Dicle University, 21280 Diyarbakir, Turkey
2Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, 34104 Istanbul, Turkey

Received 1 May 2013; Accepted 16 September 2013

Academic Editor: Terri L. Young

Copyright © 2013 Abdullah Kursat Cingu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To investigate if there is a prognostic implication of the presence of cellular debris in the anterior vitreous in patients with Behçet's disease (BD) without any ocular symptoms. Methods. One hundred and twenty eyes of 60 patients with BD were included in the study. The eyes were divided into two groups according to the presence of cellular debris in the anterior vitreous. The first group included 54 eyes which were cellular debris (+) (group A), and the second group included 66 eyes which were cellular debris (−) (group B). Fluorescein angiography (FA) was performed to all patients following routine ocular examination. Patients were called for the six monthly control visits to investigate possible new ocular involvement during followup. The Kaplan-Meier method was used to estimate survival curves. Results. Seven eyes (13%) in group A and four eyes (6.1%) in group B showed optic disc hyperfluorescence on FA ( ). None of the eyes with disc hyperflourescence on initial examination developed uveitis attacks in their followup. In Kaplan-Meier survival analysis there was a significant difference between the groups (group A 20.6% and group B 4.2%) by means of ocular involvement during their followup (log-rank = 6.85, ). Conclusions. Presence of cellular debris in the anterior vitreous may have prognostic implications in patients with BD screened for ocular involvement.