Journal of Ophthalmology / 2013 / Article / Tab 1

Research Article

Systems Biology Profiling of AMD on the Basis of Gene Expression

Table 1

Description of AMD phenotypic subtypes according to Newman et al. [1]. Abbreviated names in the first column are used in labeling the cladograms’ legends in Figures 1 and 2.

AMD phenotypeAlternative nameDescription

MD1Pre-AMDHard macular drusen (<63 μm) only

MD2 Subclinical
Soft, distinct macular drusen (>63 μm)
Macular pigmentary irregularities without soft drusen

Soft, indistinct (>125 μm) or reticular macular drusen
Soft distinct macular drusen (>63 μm) with pigmentary changes
Soft indistinct macular drusen with pigmentary changes

GA Geographic atrophySharply demarcated area of apparent absence of the RPE (>175 μm) involving central macular region

CNVWet AMDSubretinal choroidal neovascularization

GA/CNVGeographic atrophy with choroidal neovascularization

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