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Journal of Ophthalmology
Volume 2013 (2013), Article ID 463710, 5 pages
Clinical Study

Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension

1Department of Ophthalmology, The University of Hong Kong, Hong Kong
2Department of Ophthalmology, Queen Mary Hospital, Hong Kong
3Department of Family Medicine, Hospital Authority, Hong Kong
4COphth Eye Institute, The University of Hong Kong, Room 301, Level 3, Block B, 100 Cyberport Road, Cyberport 4, Hong Kong

Received 15 November 2012; Accepted 21 December 2012

Academic Editor: Michel Eid Farah

Copyright © 2013 Rita A. Gangwani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with  mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). Results. The mean age of the subjects was years, and the male:female ratio was 92 : 108. All patients were hypertensive with a mean blood pressure (BP) of  mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. Conclusion. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type.