Long-Term Followup Comparing Two Treatment Dosing Strategies of 125I Plaque Radiotherapy in the Management of Small/Medium Posterior Uveal Melanoma
Table 4
Complications from iodine-125 plaque irradiation at 10 years.
Complication
Number of cases (%)
Mean time interval from treatment (months ± standard dev.)
values (Pearson’s chi-squared test)
Radiation retinopathy
45
27 ± 15
Group 1
14 (20)
29 ± 18
<0.001
Group 2
31 (78)
25 ± 10
Radiation papillopathy
23
29 ± 16
Group 1
11 (20)
29 ± 20
0.261
Group 2
12 (30)
29 ± 16
Cataract
13
29 ± 22
Group 1
4 (7)
33 ± 22
0.04
Group 2
9 (23)
27 ± 23
Strabismus
14
5 ± 7
Group 1
6 (11)
2 ± 2
0.54
Group 2
8 (20)
7 ± 9
Vitreous hemorrhage
7
23 ± 20
Group 1
2 (4)
20 ± 16
0.19
Group 2
5 (12)
25 ± 23
Exudative RD
3
38 ± 18
Group 1
1 (2)
59
0.18
Group 2
2 (5)
28 ± 1
Overall treatment-related complications*
33
Group 1
14 (27)
0.00053
Group 2
39 (98)
*Patients experiencing one or more of the following treatment-related complications: radiation retinopathy, radiation papillopathy, visually significant cataract, or vitreous hemorrhage.
**There were no cases of neovascular glaucoma.
