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Journal of Ophthalmology
Volume 2013, Article ID 630481, 6 pages
Clinical Study

Is Hyperopia an Important Risk Factor for PACG in the Dutch Population?—A Case Control Study

The Rotterdam Ophthalmic Institute, The Rotterdam Eye Hospital, P.O. Box 70030, 3000 LM Rotterdam, The Netherlands

Received 2 July 2013; Accepted 14 August 2013

Academic Editor: Edward Manche

Copyright © 2013 Saskia H. M. van Romunde et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. To determine if hyperopia is a risk factor for primary angle-closure glaucoma (PACG) in the Dutch population and to identify other biometrical parameters as risk factors for PACG including axial length (AL), anterior chamber depth (ACD), and values. Methods. The study population consisted of PACG patients that had undergone a laser peripheral iridotomy (LPI). The control group consisted of age- and gender-matched cataract patients. The main outcome was hyperopia (spherical equivalent ≥+0.5 dioptres) measured with IOL Master or autorefractor. Refractive error, ACD, AL, and values were tested with a Mann-Whitney test and by logistic regression. Results. 117 PACG patients and 234 controls were included (mean age = 80 years ± 3.6). The prevalence of hyperopia in patients and controls was 69.6% and 61.1%, respectively (Fisher’s test ). Mann-Whitney test showed no statistically significant relation with refractive error ( ) or values ( ). In contrast, ACD and AL were statistically significant ( ). Tested with logistic regression, only ACD was a significant predictor of PACG ( ). Conclusion. There was no statistically significant correlation between refractive error and PACG. ACD was strongly correlated, though, with PACG, whereas AL turned out to be a less significant risk factor.