RNA Interference Targeting Snail Inhibits the Transforming Growth Factor β2-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells

Table 1

siRNA sequences for snail targeting and negative control.

siRNA; duplex	siRNA duplex sequences (5′-3′)
P1	Sense:	GAAUGUCCCUGCUCCACAAGCdTdT
	Antisense:	GCUUGUGGAGCAGGGACAUUCdTdT
P2	Sense:	GCGAGCUGCAGGACUCUAAUCdTdT
	Antisense:	GAUUAGAGUCCUGCAGCUCGCdTdT
P3	Sense:	CCUUCGUCCUUCUCCUCUACUdTdT
	Antisense:	AGUAGAGGAGAAGGACGAAGGdTdT
P4	Sense:	CAGAUGUCAAGAAGUACCAGUdTdT
	Antisense:	ACUGGUACUUCUUGACAUCUGdTdT
P5	Sense:	UUCUCCGAACGUGUCACGUdTdT
	Antisense:	ACGUGACACGUUCGGAGAAdTdT

Four siRNAs (P1–P4) were designed from the coding sequence of the human Snail gene. The siRNA duplex sequences are listed. A nonspecific, scrambled siRNA duplex as negative control (P5) was used as a control.