Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography
Table 2
Comparison of mean ± standard deviation (95% confidence interval) SD-OCT parameters between eyes with and without misalignments in any of the 4 sectors.
SD-OCT
AE ()
MAE ()
value†
AT (µm)
88.0 ± 14.3 (CI 59.9–116.0)
87.5 ± 15.3 (CI 57.5–117.5)
0.407
Quadrant, (µm)
Superior
109.1 ± 24.2 (CI 61.6–156.5)
106.9 ± 27.8 (CI 52.4–161.4)
0.197
Nasal
70.5 ± 10.3 (CI 50.3–90.6)
70.0 ± 12.6 (CI 43.3–94.7)
0.607
Inferior
109.1 ± 24.6 (CI 60.8–157.3)
109.6 ± 25.1 (CI 60.4–158.8)
0.712
Temporal
62.9 ± 10.9 (CI 41.5–84.2)
63.4 ± 12.1 (CI 39.7–87.1)
0.339
Clock-hour, (µm)
1
97.9 ± 26.0 (CI 46.9–148.8)
96.4 ± 30.8 (CI 36.0–156.8)
0.481
2
82.0 ± 14.5 (CI 53.5–110.4)
82.0 ± 17.4 (CI 47.9–116.1)
0.960
3
61.0 ± 10.8 (CI 39.8–82.1)
60.1 ± 13.5 (CI 33.6–86.6)
0.453
4
68.4 ± 12.6 (CI 43.7–93.0)
68.0 ± 13.6 (CI 41.3–94.7)
0.723
5
90.7 ± 22.9 (CI 45.8–135.5)
93.2 ± 27.2 (CI 39.9–146.5)
0.147
6
118.4 ± 31.8 (CI 56.0–180.7)
118.1 ± 32.3 (CI 54.8–181.4)
0.822
7
118.4 ± 31.9 (CI 55.8–180.9)
116.8 ± 29.8 (CI 58.4–175.1)
0.269
8
64.2 ± 14.1 (CI 36.5–91.8)
64.9 ± 17.3 (CI 31.0–98.8)
0.503
9
52.8 ± 14.0 (CI 25.3–80.2)
53.5 ± 14.2 (CI 25.7–81.3)
0.382
10
71.8 ± 14.0 (CI 44.3–99.2)
71.7 ± 13.6 (CI 45.0–98.4)
0.975
11
115.0 ± 29.5 (CI 57.1–172.8)
113.6 ± 28.8 (CI 57.2–170.0)
0.188
12
114.8 ± 34.7 (CI 46.7–182.8)
110.6 ± 39.1 (CI 34.0–187.2)
0.175
Signal strength
8.0 ± 0.7 (CI 6.6–9.3)
8.1 ± 0.7 (CI 6.7–9.5)
0.277
SD-OCT = spectral domain optical coherence tomography; AE = aligned exam; MAE = misaligned exam; AT = average thickness; CI = confidence interval. †Student’s -test.
