Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography
Table 3
Comparison of mean ± standard deviation (95% confidence interval) SD-OCT parameters between eyes with and without misalignments in the superior area (sectors 1 and 2).
SD-OCT
AE ()
MAE ()
value†
AT (µm)
85.2 ± 13.7 (CI 55.6–109.4)
84.2 ± 14.8 (CI 55.2–113.2)
0.351
Quadrant, (µm)
Superior
106.3 ± 24.8 (CI 57.7–154.9)
101.7 ± 28.9 (CI 45.1–158.3)
0.084
Nasal
69.3 ± 7.8 (CI 54.0–84.6)
68.0 ± 11.7 (CI 45.1–90.9)
0.444
Inferior
104.1 ± 22.2 (CI 60.6–147.6)
105.6 ± 22.5 (CI 61.5–149.7)
0.412
Temporal
61.0 ± 11.0 (CI 39.4–82.6)
61.7 ± 11.1 (CI 39.9–83.5)
0.145
Clock-hour, (µm)
1
94.3 ± 26.5 (CI 42.4–146.2)
89.7 ± 29.6 (CI 37.6–141.8)
0.155
2
80.2 ± 11.0 (CI 58.5–101.7)
79.7 ± 16.1 (CI 48.1–111.3)
0.814
3
59.5 ± 9.1 (CI 41.7–77.3)
58.2 ± 14.7 (CI 29.4–87.0)
0.531
4
67.8 ± 11.8 (CI 44.7–90.9)
66.4 ± 11.3 (CI 44.3–88.5)
0.385
5
85.8 ± 20.8 (CI 45.0–126.6)
87.0 ± 20.4 (CI 47.0–127.0)
0.510
6
111.8 ± 30.1 (CI 52.8–170.8)
114.4 ± 30.0 (CI 55.6–173.2)
0.327
7
114.9 ± 32.4 (CI 51.5–178.5)
115.4 ± 30.9 (CI 54.8–176.0)
0.753
8
62.5 ± 13.1 (CI 36.8–8.2)
62.7 ± 13.2 (CI 36.8–88.6)
0.876
9
50.2 ± 8.3 (CI 34.9–66.5)
51.6 ± 9.7 (CI 32.6–70.6)
0.050
10
70.4 ± 16.6 (CI 37.9–102.9)
70.9 ± 16.3 (CI 39.0–102.8)
0.548
11
113.4 ± 30.1 (CI 54.4–172.4)
113.4 ± 30.2 (CI 4.2–172.6)
0.979
12
111.4 ± 34.5 (CI 43.8–179.0)
101.7 ± 39.7 (CI 23.9–179.5)
0.043+
Signal strength
8.1 ± 0.7 (CI 6.7–9.5)
8.2 ± 0.6 (CI 7.0–9.4)
0.255
SD-OCT = spectral domain optical coherence tomography; AE = aligned exam; MAE = misaligned exam; AT = average thickness; CI = confidence interval. value <0.05. Student’s -test.
