Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography
Table 5
Comparison of mean ± standard deviation (95% confidence interval) SD-OCT parameters between eyes with and without misalignments within the measurement ring (sectors 2 and 3).
SD-OCT
AE ()
MAE ()
value†
AT (µm)
88.5 ± 14.5 (CI 60.1–116.9)
88.6 ± 15.1 (CI 59.0–118.2)
0.890
Quadrant, (µm)
Superior
108.3 ± 21.0 (CI 67.1–149.5)
107.8 ± 23.9 (CI 61.0–154.6)
0.735
Nasal
71.7 ± 11.0 (CI 50.1–93.3)
72.4 ± 11.4 (CI 50.1–94.7)
0.383
Inferior
110.4 ± 26.2 (CI 58.5–162.3)
110.8 ± 26.6 (CI 58.7–162.9)
0.831
Temporal
63.3 ± 12.2 (CI 39.4–87.2)
63.5 ± 13.6 (CI 38.6–92.0)
0.844
Clock-hour, (µm)
1
96.1 ± 23.3 (CI 50.4–141.8)
97.2 ± 27.8 (CI 42.7–151.7)
0.601
2
83.8 ± 16.5 (CI 51.0–115.6)
84.6 ± 17.2 (CI 50.9–118.3)
0.583
3
62.7 ± 11.2 (CI 40.7–84.7)
62.9 ± 11.1 (CI 41.1–84.7)
0.821
4
68.5 ± 11.9 (CI 45.2–91.8)
69.7 ± 13.7 (CI 42.8–96.6)
0.301
5
92.3 ± 23.1 (CI 47.0–137.6)
95.8 ± 29.3 (CI 38.4–153.2)
0.122
6
122.2 ± 34.3 (CI 55.0–189.4)
121.7 ± 35.4 (CI 52.3–191.1)
0.813
7
116.9 ± 32.3 (CI 53.6–180.2)
114.8 ± 29.2 (CI 57.6–172.0)
0.262
8
64.1 ± 14.9 (CI 34.9–93.3)
64.6 ± 19.2 (CI 27.0–102.2)
0.716
9
53.3 ± 16.1 (CI 21.7–84.9)
53.5 ± 16.3 (CI 21.6–85.4)
0.868
10
72.6 ± 14.8 (CI 43.6–101.6)
72.2 ± 14.3 (CI 44.2–100.2)
0.656
11
116.5 ± 29.0 (CI 59.7–173.3)
114.7 ± 28.9 (CI 58.1–171.3)
0.185
12
112.3 ± 27.1 (CI 59.2–165.4)
111.3 ± 32.3 (CI 48.0–174.6)
0.711
Signal strength
8.0 ± 0.7 (CI 6.6–9.4)
8.1 ± 0.8 (CI 6.5–9.7)
0.378
SD-OCT = spectral domain optical coherence tomography; AE = aligned exam; MAE = misaligned exam; AT = average thickness; CI = confidence interval. †Student’s -test.
