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Journal of Ophthalmology
Volume 2014 (2014), Article ID 459136, 7 pages
http://dx.doi.org/10.1155/2014/459136
Review Article

Examining the Choroid in Ocular Inflammation: A Focus on Enhanced Depth Imaging

1Moorfields Eye Hospital, City Road, London, EC1V2PD, UK
2UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK

Received 21 November 2013; Accepted 21 May 2014; Published 16 June 2014

Academic Editor: Vishali Gupta

Copyright © 2014 Abeir Baltmr et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The choroid is the vascular layer that supplies the outer retina and is involved in the pathogenesis of several ocular conditions including choroidal tumors, age related macular degeneration, central serous chorioretinopathy, diabetic retinopathy, and uveitis. Nevertheless, difficulties in the visualization of the choroid have limited our understanding of its exact role in ocular pathology. Enhanced depth imaging optical coherent topography (EDI-OCT) is a novel, noninvasive technique that is used to evaluate choroidal thickness and morphology in these diseases. The technique provides detailed objective in vivo visualization of the choroid and can be used to characterize posterior segment inflammatory disorders, monitor disease activity, and evaluate efficacy of treatment. In this review we summarize the current application of this technique in ocular inflammatory disorders and highlight its utility as an additional tool in monitoring choroidal involvement in ocular inflammation.