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Journal of Ophthalmology
Volume 2014, Article ID 468653, 7 pages
Clinical Study

Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity

1Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, Turkey
2Department of Ophthalmology, Zekai Tahir Burak Women’s Health Training and Research Hospital, 06110 Ankara, Turkey
3Department of Ophthalmology, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey
4Department of Ophthalmology, Faculty of Medicine, Balıkesir University, 10145 Balıkesir, Turkey

Received 1 September 2014; Revised 22 October 2014; Accepted 13 November 2014; Published 3 December 2014

Academic Editor: Terri L. Young

Copyright © 2014 Muhammet Kazim Erol et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To examine the macular findings obtained with spectral domain optical coherence tomography (SD OCT) in infants with retinopathy of prematurity (ROP). Materials and Methods. The macular SD OCT images of 190 premature infants were analyzed. Data regarding central foveal thickness (CFT), cystoid macular edema (CME), and cyst grading were compared. The relationships of CFT with gestational age and birth weight were investigated. Results. The results were obtained from 358 eyes of 179 infants (81 females and 98 males) of a mean gestational age of weeks and a mean birth weight of  g. ROP was diagnosed in 126 eyes and CME in 139 eyes. A significantly greater percentage of eyes with ROP were found to have CME (54%) compared to eyes without ROP (31%; ). The incidence of CME was 46.3% for stage 1 ROP, 57.1% for stage 2, and 87.5% for stage 3. There was a weakly inverse correlation between CFT, gestational age, and birth weight (, ; , , resp., Spearman correlation test). Conclusions. High-quality SD OCT images can be obtained from premature infants using the iVue system. Severity and frequency of CME in premature infants increase as stage of ROP increases.