Research Article

High-Resolution In Vivo Imaging of Regimes of Laser Damage to the Primate Retina

Figure 11

Subject S6 OD histological sections of a flat mount retina nine days after exposure (1,696 J/cm2). (a) Choroid, (b) outer segment of photoreceptors, (c)-(d) junction of inner and outer segment of photoreceptors, (e) inner segment of photoreceptors, and (f) junction of inner segment and outer nuclear layer. The choroid exhibits loss of pigment as well as low numbers of macrophages, lymphocytes, and plasma cells. There is disruption of the outer segments of the photoreceptors and pigment laden macrophages (b). (c) and (d) both show the junction of inner and outer segment of photoreceptors with minimal disruption of photoreceptors and two small pigment laden macrophages. The inner segment of photoreceptors with minimal disruption of photoreceptors (linear defect is an artifact) is shown in (e). The final frame (f) is the junction of inner segment and outer nuclear layer with no detectable defect.
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(a)
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(c)
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(e)
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(f)