Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris

Table 2

Corneal topographical parameters measured with Sirius before and after treatment.

	Baseline	1 month	3 months	6 months	Follow-up
Average SimK, D
Mean ± SD	43.68 ± 1.38	43.73 ± 1.35	43.62 ± 1.37	43.58 ± 1.38	43.66 ± 1.38
		0.030^∤	0.322	0.462	0.564
SAI
Mean ± SD	0.39 ± 0.31	0.45 ± 0.33	0.44 ± 0.32	0.42 ± 0.33	0.40 ± 0.30
		0.015^∤	0.052	0.060	0.124
Thinnest CT, μm
Mean ± SD	539.51 ± 48.33	537.13 ± 46.77	535.66 ± 46.31	534.87 ± 46.23	539.46 ± 48.36
		0.014^∤	0.011^∤	0.005^∤	0.128

, value according to paired -test compared with baseline.
SimK, simulated keratometry; SAI, surface asymmetry index; CT, corneal thickness; SD, standard deviation.
^∤Statistically significant at 0.05 level.