Review Article

The Role of Microglia in Diabetic Retinopathy

Table 6

Retinal Cell Cytokines.

CytokineCondition*References

IL-1In vitro, primary microglia culture; LPS and minocycline treated; culture medium quantified (rat) Wang et al. 2005 [57]
IL-1Ex vivo, STZ treated; LPS and minocycline treated; whole retina homogenate (rat)Liu et al. 2012 [90, 91]; Yang et al. 2009 [42]; Krady et al. 2005 [56]
IL-3In vivo, vitreous quantified (mouse)Liu et al. 2012 [90, 91]
IL-6In vivo, vitreous quantified (mouse and human)Liu et al. 2012 [90, 91]; Abcouwer 2013 [69]
IL-8In vivo, vitreous quantified (mouse and human)Liu et al. 2012 [90, 91]; Abcouwer 2013 [69]
IL-10In vivo, vitreous quantified (mouse)Liu et al. 2012 [90, 91]
IL-12In vivo, vitreous quantified (mouse)Liu et al. 2012 [90, 91]
IL-18Ex vivo, STZ treated; whole retina homogenate (rat)Yang et al. 2009 [42]
TNF-In vitro, primary microglia culture; LPS and minocycline treated; AGE treated; culture medium quantified (rat)Wang et al. 2005 [57]; Krady et al. 2005 [56]
TNF-Ex vivo, LPS and minocycline treated; STZ treated; whole retina homogenate (rat)Yang et al. 2009 [42]; Krady et al. 2005 [56]

The condition column represents how cytokine level was quantified, i.e., culture medium collected; whole retina homogenate; or vitreous humor collected and assayed for cytokine production.