A 2-Year, Phase IV, Multicentre, Observational Study of Ranibizumab 0.5 mg in Patients with Neovascular Age-Related Macular Degeneration in Routine Clinical Practice: The EPICOHORT Study
Figure 2
(a) Overall mean change in BCVA over time in the first-treated eye and (b) mean change in BCVA overtime based on the number of injections in the first-treated eye (safety set, LOCF). Safety set was defined as all those patients who were treated with at least one dose of ranibizumab and who had at least one safety assessment after study entry and no protocol deviations that warranted exclusion. Baseline VA results were recorded for 680 patients. Month 24 results were evaluated for 673 patients using the LOCF approach. BCVA: best-corrected visual acuity; LOCF: last observation carried forward.
