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Journal of Ophthalmology
Volume 2014, Article ID 905129, 6 pages
Research Article

Assessment of Corneal Biomechanical Properties and Intraocular Pressure in Myopic Spanish Healthy Population

1Department of Ophthalmology, Lozano Blesa University Clinic Hospital, Zaragoza, Spain
2Department of Ophthalmology, Quirón University Hospital, Zaragoza, Spain
3Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain
4Aragón Institute for Engineering Research (I3A), University of Zaragoza, CIBER on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Zaragoza, Spain
5Department of Ophthalmology, Arnau de Vilanova University Hospital and IRB-Lleida, Avenida Rovira Roure 80, Lleida, Spain

Received 13 November 2013; Accepted 10 January 2014; Published 25 February 2014

Academic Editor: Cristina Peris-Martinez

Copyright © 2014 María A. del Buey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population. Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann correlated intraocular pressure (IOP), and corneal compensated IOP (IOPcc) were measured using the ocular response analyzer (ORA) in 312 eyes of 177 Spanish subjects aged between 20 and 56 years. Refraction was expressed as spherical equivalent (SE), which ranged from 0 to −16.50 diopters (D) (mean:  D). Subjects were divided into four groups according to their refractive status: group 1 or control group: emmetropia ( ); group 2: low myopia (  D); group 3: moderate myopia (  D); and group 3: high myopia (SE greater than −6.00 D). We analyzed the relationship between corneal biomechanics measured with ORA and SE. Results. CH in the emmetropia, low myopia, moderate myopia, and high myopia groups was , , , and  mmHg, respectively. CH in the highly myopic group was significantly lower than that in the emmetropic group ( ) and low myopic group ( ); however, there were no differences with the moderate myopic group ( ). There were no statistically significant differences regarding IOP among the four groups ( ); nevertheless, IOPcc was significantly higher in the moderately myopic (  mmHg) and highly myopic (  mmHg) groups than in the emmetropia (  mmHg) and low myopia groups (  mmHg). No correlation between age and the measured parameters was found. CH and IOPcc were weakly but significantly correlated with SE ( , and , , resp.). Conclusions. Present study showed only a very weak, but significant, correlation between CH and refractive error, with CH being lower in both moderately and highly myopic eyes than that in the emmetropic and low myopic eyes. These changes in biomechanical properties of the cornea may have an impact on IOP measurement, increasing the risk of glaucoma.