Comparison of Latanoprost/Timolol with Carbonic Anhydrase Inhibitor and Dorzolamide/Timolol with Prostaglandin Analog in the Treatment of Glaucoma

Table 1

Patient background.

(a)

	Group 1	Group 2	𝑃
Cases	55 cases	57 cases	—
Ratio of male and female	31 : 24	26 : 31	0.2648
Age	66.2±12.4 years old	67.1±12.4 years old	0.7161
	32~85 years old	27~85 years old
Disease type
Primary open-angle glaucoma	40 cases	44 cases	0.8194
Normal tension glaucoma	12 cases	11 cases
Ocular hypertension	3 cases	2 cases
IOP before the change	16.1±3.4 mmHg	15.6±3.2 mmHg	0.367
	10~24 mmHg	10~23 mmHg
MD value before the change	−10.85±8.81 dB	−10.32±7.77 dB	0.8772
	−33.15~−0.13 dB	−21.73~−0.09 dB

(b)

	Used eye drops	Group 1	Group 2	𝑃
		55 cases	57 cases	—
Before the change	PG analogs
	Latanoprost	52	44	0.0139
	Travoprost	—	7
	Tafluprost	3	3
	Bimatoprost	—	3
	β-blocker
	Timolol	51	39	0.0016
	Carteolol	4	18
	CAI
	Dorzolamide	13	38	<0.0001
	Brinzolamide	42	19
After the change	PG analogs
	Latanoprost	—	44	—
	Travoprost	—	7
	Tafluprost	—	3
	Bimatoprost	—	3
	β-blocker
	Timolol	—	—	—
	Carteolol	—	—
	CAI
	Dorzolamide	13	—	—
	Brinzolamide	42	—
	Fixed-combination eye drops
	Latanoprost/timolol	55	—	—
	Dorzolamide/timolol	—	57	—