Journal of Ophthalmology

Clinical Study

Clinical Significance of Optic Disc Progression by Topographic Change Analysis Maps in Glaucoma: An 8-Year Follow-Up Study

Table 2

Comparison of baseline and enrollment descriptive characteristics, in TCA-progressed (based on HRT TCA status at enrollment) and TCA-stable eyes/patients.


	TCA status at enrollment
	TCA-stable	TCA-progressed	Overall	value
	Median (IQR)	Median (IQR)	Median (IQR)	value

Age at baseline (yrs)	55.3 (51.0, 61.6)	57.1 (53.3, 60.8)	56.5 (51.4, 60.8)	0.39
Age at enrollment (yrs)	59.2 (54.2, 65.5)	60.7 (58.3, 65.5)	60.3 (56.4, 65.5)	0.29
Preenrollment followup (yrs)	3.5 (2.8, 4.5)	4.4 (3.2, 5.3)	3.9 (3.1, 5.0)	0.09
VF exams, preenrollment period ()	5 (4, 6), range: 3–8	5 (4, 6), range: 3–11	5 (4, 6), range: 3–11	0.16
VF exams, prospective period ()	7 (6, 8), range: 3–13	7 (5.25, 8), range: 3–9	7 (6, 8), range: 3–13	0.36
HRT exams, preenrollment period ()	6 (5, 6), range: 4–10	6 (5, 7), range: 4–10	6 (5, 7), range: 4–10	0.11
HRT exams, prospective period ()	7 (5, 8), range: 2–11	7 (6, 8), range: 2–10	7 (6, 8), range: 2–11	0.14
CCT (μm)	550.0 (525.0, 577.0)	548.0 (531.0, 565.0)	548.0 (530.0, 570.0)	0.96
MD at baseline (dB)	−1.1 (−2.0, 0.1)	−1.6 (−3.5, 0.0)	−1.2 (−3.1, 0.0)	0.37
PSD at baseline (dB)	1.6 (1.3, 2.5)	1.9 (1.4, 2.8)	1.8 (1.4, 2.6)	0.22
VFI at baseline (%)	99.0 (98.0, 100.0)	98.0 (95.0, 99.0)	99.0 (96.0, 100.0)	0.17
GHT at baseline	1.0 (1.0, 3.0)	2.0 (1.0, 3.0)	1.0 (1.0, 3.0)	0.32
MRA at baseline	2.0 (1.0, 3.0)	2.0 (1.0, 3.0)	2.0 (1.0, 3.0)	0.27
MD at enrollment (dB)	−0.78 (−2.64, 0.15)	−0.99 (−2.7, 0.08)	−0.80 (−2.79, 0.03)	0.48
PSD at enrollment (dB)	1.53 (1.39, 2.08)	1.53 (1.39, 2.08)	1.77 (1.4, 2.4)	0.06
VFI at enrollment (%)	99 (98.5, 100)	98 (96, 99)	99 (97, 99)	0.09
Mean HRT topography SD at baseline (µm)	17 (13.5, 22.5)	16 (11.0, 21.0)	16 (12, 21)	0.27

IQR: interquartile ranges; CCT: central corneal thickness; VF: visual field; MD: mean deviation; PSD: pattern standard deviation; VFI: visual field index; SD: standard deviation; Stdev: standard deviation; GHT: glaucoma hemifield test (1.0: within normal limits, 2.0: borderline, and 3.0: outside normal limits); MRA: moorfields regression analysis (1.0: within normal limits, 2.0: borderline, and 3.0: outside normal limits).