Clinical Study
Safety and Efficacy of Adding Fixed-Combination Brinzolamide/Timolol Maleate to Prostaglandin Therapy for Treatment of Ocular Hypertension or Glaucoma
Table 2
Adverse events (safety population).
| | Episodes, (%)
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| Patients experiencing 1 adverse event, (%) | 21 (44.7) | Adverse event severity | | Mild | 23 (82.1) | Moderate | 4 (14.3) | Severe | 1 (3.6) | Adverse event | | Headache | 3 (10.7) | Allergic conjunctivitis | 1 (3.6) | Allergic rhinitis | 1 (3.6) | Ankle pain | 1 (3.6) | Burning/eyelid swelling | 1 (3.6) | Blurred vision | 1 (3.6) | Conjunctival discomfort | 1 (3.6) | Corneal superficial keratitis | 1 (3.6) | Crusting of lashes | 1 (3.6) | Dry eye | 1 (3.6) | Eye pain | 1 (3.6) | Lid erythema | 1 (3.6) | Metallic taste | 1 (3.6) | Ocular foreign body sensation | 1 (3.6) | Pseudostenocardia | 1 (3.6) | Punctate keratopathy | 1 (3.6) | Rhinitis sicca | 1 (3.6) | Scheduled knee total endoprosthesis due to gonarthrosis | 1 (3.6) | Stomachache | 1 (3.6) | Subjective poorer vision | 1 (3.6) | Tinnitus | 1 (3.6) | Tiredness and insomnia | 1 (3.6) | Trace keratitis | 1 (3.6) | Upper respiratory infection | 1 (3.6) | Worsening of dorsal pain | 1 (3.6) | Unknown | 1 (3.6) |
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Calculated as the percentage of patients in the safety population (). Serious adverse event. A description was not available for 1 event in 1 patient.
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