The Fundus Autofluorescence Spectrum of Punctate Inner Choroidopathy

Figure 3

Fundus photography (a, f), SW-FAF (b, g), FA (c, h), ICGA (d, i), and SD-OCT (e, j) of the right eye of a 24-year-old female at the initial visit and 5 weeks later. At the initial visit, her BCVA was 0.2. (a) There were scattered yellowish spots in the upper posterior pole in addition to the yellow-gray PIC lesions. (b) Diffuse hyperautofluorescent areas were shown on SW-FAF, which tended to emerge in the macula and around the optic disc. Additionally, the hypoautofluorescent PIC lesions were surrounded by hyperautofluorescent edge. (c) FA revealed patches of hyperfluorescence, which was especially obvious in late phase and the extent was smaller than it was on SW-FAF and ICGA.The PIC lesions showed hyperfluorescent spots with slight leakage. (d) Hypocyanescent spots were indicated in the late phase of ICGA. (e) The red line (crossing a PIC lesion and hyperautofluorescent areas on SW-FAF) shown on SD-OCT was dome-shaped high reflective materials (arrow), with underlying disrupted EZ. Additionally, an active lesion (stage III) was detected. Five weeks later, the MEWDS lesions faded completely on fundus photography (f), SW-FAF (g), FA (h), and ICGA (i). Meanwhile, the dome-shaped high reflective materials on SDOCT disappeared and disruption of EZ near-completely recovered (j). The hyperautofluorescent margin of the PIC lesion faded on SW-FAF (g). The PIC lesion regressed on SD-OCT (j). Her BCVA was improved to 0.32.