The Fundus Autofluorescence Spectrum of Punctate Inner Choroidopathy

Table 1

FAF and corresponding SD-OCT, FA, and ICGA findings of punctate inner choroidopathy.

FAF		SD-OCT	FA	ICGA
SW-FAF	NIR-FAF
Hypo-AF spot with hyper-AF margin		Hump-shaped chorioretinal nodule of moderate reflectivity breaking through RPE and BM, beneath the OPL	—	—
Hypo-AF spot		Atrophic lesion: the nodule regresses from the apex toward the choroidal part, with or without RPE proliferation subclinical lesion: sub-RPE nodules penetrating BM to lift the RPE	—	—
Hypo-AF spot coexisting with diffuse hyper-AF patches	Nothing abnormal detected^†	Diffuse or multifocal disruption of EZ^†	Normal or patches of hyperfluorescence from the initial phase^†	Normal or multiple hypocyanescent spots extending from posterior pole to midperiphery on the late phase^†

BM: Bruch’s membrane; EZ: ellipsoid zone; hypo-AF: hypoautofluorescent; hyper-AF: hyperautofluorescent; OPL: outer plexiform layer; RPE: retinal pigment epithelium.
Findings in addition to PIC lesion.