Review Article
Ocular Complications in Cutaneous Lupus Erythematosus: A Systematic Review with a Meta-Analysis of Reported Cases
Table 2
Clinical features of ocular LEP in each study.
| Reference/country | Study design | Age (years)/gender | Ratio Monolateral : Bilateral | Ocular site | Ratio ANA P : N | Treatment |
| Sheehan-Dare and Cunliffe (1988), UK [22] | CR | 47 m | Monolateral | Periorbital edema | Positive; speckled pattern | Prednisolone 40 mg |
| Magee et al. (1991), USA [25] | CR | 41 m | Monolateral | Periorbital swelling and proptosis | — | Hydroxychloroquine and prednisone |
| Inuzuka et al. (2001), Japan [56] | CR | 71 f | Bilateral | Eyelid plaque and subcutaneous nodules | Positive | Prednisolone 30 mg |
| Kao et al. (2010), USA [55] | CR | 76 m | Monolateral | Enophthalmos | Positive; diffuse pattern | Prednisone 60 mg |
| Sudhakar et al. (2012), USA [54] | CR | 51 f | Monolateral | Orbit and periorbit inflammation associated with CRAO | — | — |
| Ohsie et al. (2012), USA [53] | CR | 18 f | Monolateral | Panniculitis involving orbit and periorbit tissue | Negative | Corticosteroid and mycophenolate mofetil |
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CR: case report; P: positive; N: negative; LEP: lupus erythematosus profundus; CRAO: central retinal artery occlusion. Dosage not specified.
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