ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa

Table 1

Demographic, ocular parameters, and ET-1 plasma levels in patients with retinitis pigmentosa and healthy controls.

	Retinitis pigmentosa	Controls
Age, years	33.8 ± 7.3	36.0 ± 6.8	0.155
Visual acuity, decimals	0.95 ± 0.07	0.97 ± 0.04	0.235
IOP, mmHg	15.8 ± 2.5	15.6 ± 2.3	0.81
SAP-PSD, dB	6.09 ± 4.22	1.98 ± 0.98	0.001
SAP-MD, dB	−7.90 ± 1.75	−1.95 ± 0.83	0.006
ERG b-wave, V	45.08 ± 8.24	65.36 ± 9.84	0.002
ERG a-wave, V	28.13 ± 5.77	38.16 ± 5.57	0.019
ET-1, pg/mL	2.143 ± 0.258	1.219 ± 0.236	0.002
Choroidal thickness, m	226.75 ± 76.37	303.9 ± 39.87	0.023
Aqueous flare, pc/ms	10.51 ± 3.97	5.66 ± 1.29	0.0001

Note: values are presented as means ± SD; = 24 per group.
IOP = intraocular pressure; SAP = standard automated perimetry; PSD = pattern standard deviation; MD = mean defect; dB = decibel; ERG = electroretinogram; V = microvolt; ET-1 = endothelin-1; pg/mL = picogram/milliliter; m = micrometer; pc/ms = photon counts/millisecond.