Review Article

The Effect of Hormone Replacement Therapy on Dry Eye Syndrome Evaluated with Schirmer Test and Break-Up Time

Figure 3

Forest plot of Schirmer score change without anesthetics for the effect of HRT on DES patients. Study of Affinito et al. (2003b) indicates that the data were obtained without anesthetics. Study of Scuderi et al. (2012a) indicates that the data were extracted with the HRT group and control group, and study of Scuderi et al. (2012b) indicates that the data were extracted from reversed groups; that is, the HRT group and control group were reversed after a washout period. HRT: hormone replacement therapy; SD: standard deviation; CI: confidence interval; and IV: inverse variance.