Journal of Ophthalmology / 2015 / Article / Tab 1

Research Article

Comparison of United States and Canadian Glaucoma Medication Costs and Price Change from 2006 to 2013

Table 1

Retail cash price cost comparison of glaucoma topical medications in the USA and Canada.

Product name Active ingredient Conc.
%
Size
mL
Price per bottle Measured
volume1
mL
Drops per mL1 Bottles per
year
Wastage
adjustment2
Yearly cost Additional yearly
cost in USA
$
Costco in USA
$US
Costco in Canada
$Cdn
Costco in USA
$US
Costco in Canada
$Cdn

Prostaglandins
Brand
 LumiganBimatoprost0.015228.6964.615.2932.234.31.211,184.78334.70850.08
 Travatan ZTravoprost0.0045218.1965.355.0333.584.31.211,141.02341.74799.29
 Xalatan3Latanoprost0.0055222.2468.806.2629.663.91.211,057.27327.31729.96
Generic
 Latanoprost4Latanoprost0.005533.4028.716.2629.663.91.21158.89136.5822.32
β-Blockers
Brand
 Betoptic SBetaxolol0.2510191.7429.409.7626.345.71.211,317.61202.031,115.58
 Timoptic-XE5Timolol0.255120.6127.305.2121.626.51.21945.80214.10731.70
 Timoptic-XETimolol0.55167.2131.905.2121.626.51.211,311.22250.181,061.05
Generic
 Levobunolol5Levobunolol0.251017.7114.0810.0125.715.71.21121.5796.6724.90
 LevobunololLevobunolol0.51033.9616.4610.0125.715.71.21233.11113.02120.10
 Timolol5Timolol0.251011.9514.4610.0329.594.91.2171.1386.06
 TimololTimolol0.51013.5717.1510.0329.594.91.2180.77102.10
 Timolol-XE5Timolol-XE0.25539.3114.575.2121.626.51.21308.26114.25194.01
 Timolol-XETimolol-XE0.5541.8316.675.2121.626.51.21328.02130.69197.33
α2-Agonists
Brand
 Alphagan PBrimonidine0.1510204.6729.8610.3722.526.31.211,548.26225.861,322.40
Generic
 Brimonidine4Brimonidine0.1510169.2322.8110.3722.526.31.211,280.17172.541,107.63
 BrimonidineBrimonidine0.21015.5916.5010.2826.285.41.21101.94107.91
CAIs
Brand
 AzoptBrinzolamide1.010148.9440.3210.0429.494.91.21888.67240.57648.10
 TrusoptDorzolamide2.01087.4646.879.9823.536.21.21657.95352.61305.35
Combination
Brand
 Combigan6Brimonidine/timolol0.2–0.510206.7949.0110.3722.526.31.211,564.30370.761,193.55
 CosoptDorzolamide/timolol2.0–0.510162.2569.2610.6522.336.11.211,205.27514.48690.80
Generic
 Dorzolamide/timolol4Dorzolamide/timolol2.0–0.51018.2550.4310.6522.336.11.21135.57374.59

Fiscella et al. [10] and Rylander et al. [11].
2Iordanous et al. [13], Platt et al. [14], and Lee and Hutnik [12].
3Only 2.5 mL bottle available so price for 5 mL is 2.5 mL × 2.
4Assumed equivalent brand name’s measured volume and drops per mL.
5Assumed equivalent 0.5%’s measured volume and drops per mL.
6Assumed Alphagan P’s measured volume and drops per mL.

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