Research Article

Blood Pressure and Heart Rate Variability to Detect Vascular Dysregulation in Glaucoma

Table 1

Description of parameters calculated by time domain analysis. Parameters were calculated for heart rate and systolic and diastolic blood pressure.

MethodParameterDescription

Time domainMEANNNMean value of all NN intervals
SDNNStandard deviation of all NN intervals
CVNNCoefficient of variation of all NN intervals
SDANN1Standard deviation of the averages of NN intervals in all 1-minute segments of the entire recording
SDANN5Standard deviation of the averages of NN intervals in all 5-minute segments of the entire recording
SDANN10Standard deviation of the averages of NN intervals in all 10-minute segments of the entire recording
RMSSDSquare root of the mean squared differences of successive NN intervals
PNN50Proportion derived by dividing the number of interval differences of successive NN intervals greater than 50 ms by the total number of NN intervals
PNN100Proportion derived by dividing the number of interval differences of successive NN intervals greater than 100 ms by the total number of NN intervals
PNN200Proportion derived by dividing the number of interval differences of successive NN intervals greater than 200 ms by the total number of NN intervals
PNNL10Portion of NN interval differences <10 ms in all NN intervals
PNNL20Portion of NN interval differences <20 ms in all NN intervals
PNNL30Portion of NN interval differences <30 ms in all NN intervals
PNNL50Portion of NN interval differences <50 ms in all NN intervals
RENYI2Renyi entropy of the histogram with (order) alpha = 2
RENYI4Renyi entropy of the histogram with alpha = 4
RENYI025Renyi entropy of the histogram with alpha = 0.25
SHANNONShannon entropy of the histogram