Research Article

Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics

Table 1

Gene Ontology cellular compartment analysis.

AnnotationsProteinsNGRHyp

GO:0005737: cytoplasm 110653021.8 × 10−2891.3 × 10−286
GO:0005634: nucleus 80354411.2 × 10−1012.14 × 10−99
GO:0005829: cytosol 63321464.4 × 10−2341.6 × 10−231
GO:0016020: membrane 55140651.2 × 10−529.2 × 10−51
GO:0005886: plasma membrane 47235753.1 × 10−411.4 × 10−39
GO:0005739: mitochondrion 45313941.8 × 10−1814.3 × 10−179
GO:0016021: integral to membrane 40544006.1 × 10−85.2 × 10−7
GO:0005730: nucleolus 32014616.2 × 10−768.8 × 10−74
GO:0005622: intracellular 23019628.8 × 10−141.6 × 10−12
GO:0005783: endoplasmic reticulum 22210002.8 × 10−532.5 × 10−51
GO:0005654: nucleoplasm 2158914.3 × 10−584.36 × 10−56
GO:0005856: cytoskeleton 1878461.4 × 10−448.4 × 10−43
GO:0005794: Golgi apparatus 1749583.5 × 10−301.2 × 10−28
GO:0005576: extracellular region 17019130.0030.008
GO:0005789: endoplasmic reticulum membrane 1406427.3 × 10−332.7 × 10−31
GO:0005625: soluble fraction 1203904.1 × 10−442.2 × 10−42
GO:0048471: perinuclear region of cytoplasm 1154173.3 × 10−371.4 × 10−35
GO:0005743: mitochondrial inner membrane 1133082.8 × 10−502.0 × 10−48
GO:0005759: mitochondrial matrix 1042013.3 × 10−643.9 × 10−62
GO:0005624: membrane fraction 985232.0 × 10−185.0 × 10−42
GO:0005615: extracellular space 967842.5 × 10−72.1 × 10−6
GO:0005887: integral to plasma membrane 9410160.0080.02
GO:0030054: cell junction 854755.9 × 10−151.1 × 10−13
GO:0005840: ribosome 781741.5 × 10−427.1 × 10−41
GO:0000139: Golgi membrane 754202.6 × 10−134.4 × 10−12
GO:0045202: synapse 702888.86 × 10−202.4 × 10−18
GO:0030529: ribonucleoprotein complex 691322.2 × 10−431.1 × 10−41
GO:0031410: cytoplasmic vesicle 672875.2 × 10−181.3 × 10−16
GO:0005792: microsome 642797.3 × 10−171.6 × 10−15
GO:0005813: centrosome 633233.7 × 10−136.1 × 10−12
GO:0042470: melanosome 59891.1 × 10−457.0 × 10−44
GO:0005874: microtubule 592622.8 × 10−155.7 × 10−14
GO:0009986: cell surface 572979.6 × 10−121.3 × 10−10
GO:0043231: intracellular membrane-bounded organelle 562694.7 × 10−137.4 × 10−12
GO:0015629: actin cytoskeleton 541805.16 × 10−201.52 × 10−18
GO:0043234: protein complex 532172.0 × 10−154.0 × 10−14
GO:0043025: neuronal cell body 482172.1 × 10−123.2 × 10−11
GO:0005694: chromosome 482653.0 × 10−93.3 × 10−8
GO:0071013: catalytic step 2 spliceosome 47791.8 × 10−337.1 × 10−32
GO:0016607: nuclear speck 461346.8 × 10−201.9 × 10−18
GO:0005768: endosome 452803.5 × 10−72.6 × 10−6
GO:0030424: axon 431734.6 × 10−137.3 × 10−12
GO:0030425: dendrite 421821.2 × 10−111.5 × 10−20
GO:0005764: lysosome 401791.0 × 10−101.2 × 10−9
GO:0019717: synaptosome 391111.7 × 10−174.1 × 10−16
GO:0042995: cell projection 391586.9 × 10−129.8 × 10−11
GO:0022625: cytosolic large ribosomal subunit 38521.9 × 10−326.9 × 10−31
GO:0005741: mitochondrial outer membrane 371023.4 × 10−177.8 × 10−16
GO:0031012: extracellular matrix 371461.0 × 10−111.3 × 10−11
GO:0000502: proteasome complex 36603.8 × 10−261.2 × 10−24
GO:0016323: basolateral plasma membrane 351294.4 × 10−126.4 × 10−11
GO:0005681: spliceosomal complex 34751.6 × 10−194.1 × 10−18
GO:0016324: apical plasma membrane 321961.2 × 10−56.4 × 10−5
GO:0005938: cell cortex 311068.7 × 10−121.2 × 10−10
GO:0005635: nuclear envelope 311071.1 × 10−111.5 × 10−10
GO:0031965: nuclear membrane 301331.7 × 10−81.6 × 10−7
GO:0005911: cell-cell junction 29936.9 × 10−129.6 × 10−11
GO:0005788: endoplasmic reticulum lumen 291062.4 × 10−102.8 × 10−9
GO:0005925: focal adhesion 281161.0 × 10−81.1 × 10−7
GO:0030496: midbody 27733.6 × 10−136.0 × 10−12
GO:0005769: early endosome 271221.3 × 10−71.1 × 10−6
GO:0022627: cytosolic small ribosomal subunit 26362.2 × 10−226.8 × 10−21
GO:0015630: microtubule cytoskeleton 26973.2 × 10−93.4 × 10−8
GO:0045211: postsynaptic membrane 261700.00020.0009
GO:0005643: nuclear pore 25584.1 × 10−147.7 × 10−13
GO:0045121: membrane raft 251284.3 × 10−62.5 × 10−5
GO:0009897: external side of plasma membrane 251550.00010.0005
GO:0008021: synaptic vesicle 24704.7 × 10−115.7 × 10−10
GO:0005777: peroxisome 241053.4 × 10−72.6 × 10−11
GO:0014069: postsynaptic density 231071.9 × 10−61.2 × 10−5
GO:0005793: endoplasmic reticulum-Golgi intermediate compartment 22469.8 × 10−141.7 × 10−12
GO:0005819: spindle 221131.7 × 10−58.9 × 10−5
GO:0005765: lysosomal membrane 221236.4 × 10−50.0003
GO:0010008: endosome membrane 221450.00070.003
GO:0001725: stress fiber 21456.6 × 10−131.0 × 10−11
GO:0030426: growth cone 21722.0 × 10−81.9 × 10−7
GO:0043005: neuron projection 21811.9 × 10−71.6 × 10−6
GO:0005905: coated pit 20461.2 × 10−111.5 × 10−10
GO:0031901: early endosome membrane 20638.7 × 10−79.07 × 10−8
GO:0001726: ruffle 20721.1 × 10−79.2 × 10−7
GO:0030659: cytoplasmic vesicle membrane 20831.3 × 10−68.9 × 10−6
GO:0030027: lamellipodium 201013.0 × 10−50.0002

Cellular compartments identified by at least 20 proteins are included.
Proteins: number of proteins identified in cellular compartment.
NGR: number of annotated proteins in the reference list.
Hyp: hypergeometric value.
: corrected hypergeometric value.