Expression of HGF and c-Met Proteins in Human Keratoconus Corneas

Figure 4

Frequency histograms for HGF (a) and c-Met (b) expression in KC and control corneas (combined score of staining intensity and % area coverage; range = 0 to 6). Note the right skewed distribution of HGF and c-Met immunostaining for KC corneas compared to controls. HGF staining had a combined score >3 in 7/10 (70%) KC corneas, compared to 1/6 (16%) control corneas. c-Met staining with a combined score >3 was seen in 9/10 (90%) KC corneas compared to 4/6 (66%) control corneas.

(a)

(b)