Safety and Biocompatibility of a New High-Density Polyethylene-Based Spherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits

Figure 1

Clinical evaluation follow-up after orbital implantation. The severities of regional tenderness (a), eyelid swelling (b), conjunctival hyperemia (c), and amount of exudate (d) were recorded at each time point after insertion of the MEDPOR, OCULFIT I, and OCULFIT II implants. Clinical signs were graded as none, mild, moderate, or severe according to Hackett and McDonald scoring system [19]. Clinical examinations were performed on days 1, 7, 15, 30, 45, 60, 90, 120, 150, and 180 after implantation. Bubble sizes are proportional to the number of animals.

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